小鼠永生化小胶质细胞系

背景介绍/context：

Immortalised microglial cell line (IMG) isolated from the brains of adult mice.Microglia cells share functional similarities with macrophages, and are thought to act as the primary immune cells of the central nervous system (CNS). They monitor their microenviornment and become activated upon detection of abnormal and/or offensive signals. Activated microglia have been found in inflammatory conditions such as brain/spinal cord injury, ischemic strokes, infections and neurodegenerative diseases. Recent findings indicate that microglia are also involved in learning and memory by regulating synaptic plasticity.

从成年小鼠的大脑中分离出的永生化小胶质细胞(IMG)。小胶质细胞与巨噬细胞在功能上有相似之处，被认为是中枢神经系统(CNS)的主要免疫细胞。它们监控自己的微环境，并在发现异常和/或攻击性信号时被激活。激活的小胶质细胞在炎症条件下被发现，如脑/脊髓损伤，缺血性中风，感染和神经退行性疾病。最近的研究表明，小胶质细胞也通过调节突触的可塑性参与学习和记忆。

动物种别/Organism  小鼠

组织来源 Tissue and Cell Type 大脑

形态/Morphology 贴壁生长 

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