FRO人甲状腺癌细胞（未分化）

取材于男性患者。经无支原体/STR鉴定入库。

动物种别：人

组织来源 ：甲状腺癌

形态：上皮细胞样，贴壁生长

培养基配方：

95%1640(MD0200)+5%胎牛血清(SD0200)+G/A (SD0038)

完全培养基：1640完全培养基（MD0216）

气相：空气，95%；二氧化碳，5%。 温度：37℃。

冻存条件：90%FBS(SD0200)+10%DMSO

完全冻存液：免程序降温细胞冻存液（低血清）(SD0001)

声明：产品仅科研使用。

PubMed=9348181; DOI=10.1210/endo.138.11.5509
Eijun Nishihara, Yuji Nagayama, Fumihiro Mawatari, Kunihiko Tanaka, Hiroyuki Namba, Masami Niwa, Shunichi Yamashita;
Retrovirus-mediated herpes simplex virus thymidine kinase gene transduction renders human thyroid carcinoma cell lines sensitive to ganciclovir and radiation in vitro and in vivo.
Endocrinology 138:4577-4583(1997)

PubMed=11439348; DOI=10.1038/sj.onc.1204531
Francesco Frasca, Paolo Vigneri, Veronica Vella, Riccardo Vigneri, Jean Yin-Jen Wang;
Tyrosine kinase inhibitor STI571 enhances thyroid cancer cell motile response to hepatocyte growth factor.
Oncogene 20:3845-3856(2001)

PubMed=15613457; DOI=10.1677/erc.1.00818
Masahiko Onda, Mitsuru Emi, Akira Yoshida, Shizuyo Miyamoto, Junko Akaishi, Shin-ichi Asaka, Kosuke Mizutani, Kazuo Shimizu, Munehiko Nagahama, Kouichi Ito, Toshihiro Tanaka, Tatsuhiko Tsunoda;
Comprehensive gene expression profiling of anaplastic thyroid cancers with cDNA microarray of 25 344 genes.
Endocr. Relat. Cancer 11:843-854(2004)

PubMed=16924234; DOI=10.1038/sj.onc.1209899
Wei Yu, Issei Imoto, Jun Inoue, Masahiko Onda, Mitsuru Emi, Johji Inazawa;
A novel amplification target, DUSP26, promotes anaplastic thyroid cancer cell growth by inhibiting p38 MAPK activity.
Oncogene 26:1178-1187(2007)

PubMed=18713817; DOI=10.1210/jc.2008-1102; PMCID=PMC2582569
Rebecca E. Schweppe, Joshua Paul Klopper, Christopher T. Korch, Umarani Pugazhenthi, Miriam Benezra, Jeffrey A. Knauf, James Alexander Fagin, Laura A. Marlow, John Alton Copland 3rd, Robert Christian Smallridge, Bryan R. Haugen;
Deoxyribonucleic acid profiling analysis of 40 human thyroid cancer cell lines reveals cross-contamination resulting in cell line redundancy and misidentification.
J. Clin. Endocrinol. Metab. 93:4331-4341(2008)

PubMed=25675381; DOI=10.1210/jc.2014-2764; PMCID=PMC4422887
Christina A. von Roemeling, Laura A. Marlow, Anthony B. Pinkerton, Angela Crist, James Miller, Han W. Tun, Robert Christian Smallridge, John Alton Copland 3rd;
Aberrant lipid metabolism in anaplastic thyroid carcinoma reveals stearoyl CoA desaturase 1 as a novel therapeutic target.
J. Clin. Endocrinol. Metab. 100:E697-E709(2015)