人肾小球微血管内皮细胞（HGMEC）

背景介绍/context：

   Primary Human Glomerular Microvascular Endothelial Cells，These antibody-free human primary cells were initiated by decapsulated glomeruli isolated from normal human kidney cortical tissue without the use of positive selection of antibodies人肾小球微血管内皮细胞是从正常人肾皮质组织的囊性肾小球分离提取，未经任何抗体筛选，细胞无抗性。

动物种别/Organism  人

组织来源 Tissue and Cell Type 肾皮质组织

形态/Morphology 上皮细胞样，贴壁生长

培养基和添加剂/Complete Growth Medium and Culture Conditions:

完全培养基：CultureBoost™经典细胞培养基（货号：4Z0-500）

气相：空气，95%；二氧化碳，5%。 温度：37摄氏度。

冻存液：细胞冻存液Cell Freezing Medium（4Z0-705）

人肾小球微血管内皮细胞（HGMEC）出库检测指标：

注意事项：此产品仅供科研使用

Closing the Mitochondrial Permeability Transition Pore in hiPSC-Derived Endothelial Cells Induces Glycocalyx Formation and Functional Maturation" Tiemeier et al. Stem Cell Reports, 2019

"Directed differentiation of human induced pluripotent stem cells into mature kidney podocytes and establishment of a Glomerulus Chip" Musah et al. Nature Protocols, 2018

"Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells" Sartain et al. J Biological Chemistry, 2018

"Tacrolimus Prevents von Willebrand Factor Secretion by Allostimulated Human Glomerular Endothelium" Beland et al. Am J Transplantation, 2018

"Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip" Musah et al. Nature and Biological Engineering, 2017

"The formation of quiescent glomerular endothelial cell monolayer in vitro is strongly dependent on the choice of extracellular matrix coating" Pajecka et al. Experimental Cell Research, 2017.

"The human kidney capsule contains a functionally distinct mesenchymal stromal cell population" Leuning et al. PLoS One, 2017.

"Nitrite Activates 5′AMP-Activated Protein Kinase-Endothelial Nitric Oxide Synthase Pathway in Human Glomerular Endothelial Cells" Miyamoto et al. Biol. & Pharma Bulletin, 2017.

"Circulating Fibroblast Growth Factor-2, HIV-Tat, and Vascular Endothelial Cell Growth Factor-A in HIV-Infected Children with Renal Disease Activate Rho-A and Src in Cultured Renal Endothelial Cells"  Das et al. PLoS One, 2016.

"TNF Regulates Essential Alternative Complement Pathway Components and Impairs Activation of Protein C in Human GLomerular Endothelial Cells" Sartain et al. J Immunology, 2016.

"TNF causes changes in glomerular endothelial permeability and morphology through a Rho and myosin light chain kinase-dependent mechanism" Xu et al. Physiological Reports, 2015.

"Factor VIII Is Synthesized in Human Endothelial Cells, Packaged in Weibel-Palade Bodies and Secreted Bound to ULVWF Strings" Turner and Moake, PLoS One, 2015.

"Adenosine Kinase Inhibition Protects The Kidney Against Streptozotocin-Induced Diabetes Through Anti-inflammatory and Anti-oxidant Mechanisms" Pye et al. Pharmacological Research, 2014.

SDS

ACBRI 128