SK-MEL-5人皮肤黑色素瘤细胞

人皮肤黑色素瘤细胞SK-MEL-5，又名SK-Mel-5、SKMEL5、SK-MEL5、SKMel-5、AA-Mel等。
该细胞是Takahashi T及其同事分离建系的一系列黑素瘤细胞之一。该细胞来源于一名罹患恶性黑色素瘤的24岁白人女性的皮肤组织。据报道，该细胞核型超五倍体，多数细胞染色体数目范围114-123（染色体众数=120），可在裸鼠体内成瘤。该细胞系是合适的转染宿主，并且还用于检测黑素瘤患者中黑素瘤特异性抗体的靶细胞来源。

动物种别：人

组织来源：皮肤；来自转移灶：腋窝淋巴结；疾病：恶性黑色素瘤

形态：星形，贴壁生长

培养基配方：MEM完全培养基（货号：MD0301）

气相：空气，95%；二氧化碳，5%。 温度：37℃。

冻存条件：90%FBS（SD0200)+10%DMSO

完全冻存液：免程序降温细胞冻存液（低血清）(SD0001)

声明：产品仅科研使用。

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Cancer Cell 40:835-849.e8(2022)

PubMed=38861359; DOI=10.1158/0008-5472.CAN-23-3031; PMCID=PMC11292194
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HTS384 NCI60: the next phase of the NCI60 screen.
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