MO3.13人少突胶质细胞

MO3.13细胞系是一种人少突胶质细胞系，由人肿瘤横纹肌肉瘤RD细胞系与成年人少突胶质细胞融合产生的杂交细胞系。与亲本肿瘤细胞系横纹肌肉瘤RD相比，杂交克隆MO3.13细胞系表达GalC、MBP和GFAP。MO3.13细胞系在体外环境下，能够较好地模拟少突胶质细胞的增殖与分化过程，广泛应用于相关的神经科学研究，是研究少突胶质细胞和星形胶质细胞基因表达的重要模型。

动物种别：人

组织来源：大脑组织

形态：上皮细胞样，贴壁生长

培养基配方：DMEM完全培养基（货号：MD0111）    

气相：空气，95%；二氧化碳，5%。 温度：37℃。

冻存条件：90%FBS（SD0200)+10%DMSO

完全冻存液：免程序降温细胞冻存液（低血清）(SD0001)

声明：产品仅科研使用。

PubMed=7707048; DOI=10.1002/neu.480260212
JoAnne McLaurin, Geralyn C. Trudel, Ivan T. Shaw, Jack P. Antel, Neil R. Cashman;
A human glial hybrid cell line differentially expressing genes subserving oligodendrocyte and astrocyte phenotype.
J. Neurobiol. 26:283-293(1995)

PubMed=10074188; DOI=10.1128/JVI.73.4.3338-3350.1999; PMCID=PMC104098
Nathalie Arbour, Genevieve Cote, Claude Lachance, Marc Tardieu, Neil R. Cashman, Pierre J. Talbot;
Acute and persistent infection of human neural cell lines by human coronavirus OC43.
J. Virol. 73:3338-3350(1999)

PubMed=14618099; DOI=10.1023/A:1027324230923
Mieke Buntinx, Joris Vanderlocht, Niels Hellings, Frank Vandenabeele, Ivo Lambrichts, Jef Raus, Marcel Ameloot, Piet Stinissen, Paul Steels;
Characterization of three human oligodendroglial cell lines as a model to study oligodendrocyte injury: morphology and oligodendrocyte-specific gene expression.
J. Neurocytol. 32:25-38(2003)

PubMed=24167090; DOI=10.1002/pmic.201300201
Keiko Iwata, Cecilia Cerqueira Cafe-Mendes, Andrea Schmitt, Johann Steiner, Takayuki Manabe, Hideo Matsuzaki, Peter Falkai, Christoph W. Turck, Daniel Martins-de-Souza;
The human oligodendrocyte proteome.
Proteomics 13:3548-3553(2013)

PubMed=28861932; DOI=10.1002/pmic.201700209
Juliana S. Cassoli, Caroline Brandao-Teles, Aline G. Santana, Gustavo H.M.F. Souza, Daniel Martins-de-Souza;
Ion mobility-enhanced data-independent acquisitions enable a deep proteomic landscape of oligodendrocytes.
Proteomics 17:e1700209.1-e1700209.6(2017)