SVG p12 人脑星形胶质细胞

SVG p12细胞是从8-12周龄胚胎的脑组织中分离获得的人胎儿星形胶质细胞，用复制起始点突变的SV40 DNA转染后建系。该细胞表达SV40 T抗原，易受JC病毒感染，可用于检测和培养人类嗜神经病毒等。

动物种别：人

组织来源： 脑星形胶质瘤；SV40转化

形态：成纤维细胞样，贴壁生长

培养基配方：AGM 星形胶质细胞培养基（货号：P2701）

气相：空气，95%；二氧化碳，5%。 温度：37℃。

冻存条件：90%FBS（SD0200)+10%DMSO

完全冻存液：免程序降温细胞冻存液（低血清）(SD0001)

声明：产品仅科研使用。

Patent=US4707448
Eugene O. Major;
Immortal line of human fetal glial cells.
Patent number US4707448, 17-Nov-1987

PubMed=24052414; DOI=10.1007/s11481-013-9499-8
Michael W. Ferenczy, Kory R. Johnson, Shannon M. Steinberg, Leslie J. Marshall, Maria Chiara G. Monaco-Kushner, Alexander M. Beschloss, Peter N. Jensen, Eugene O. Major;
Clonal immortalized human glial cell lines support varying levels of JC virus infection due to differences in cellular gene expression.
J. Neuroimmune Pharmacol. 8:1303-1319(2013)

PubMed=24760884; DOI=10.1128/JVI.00696-14; PMCID=PMC4054427
Stian Henriksen, Garth Daryl Tylden, Alexis Dumoulin, Biswa Nath Sharma, Hans H. Hirsch, Christine Hanssen Rinaldo;
The human fetal glial cell line SVG p12 contains infectious BK polyomavirus.
J. Virol. 88:7556-7568(2014)

PubMed=25288626; DOI=10.1128/JVI.01600-14; PMCID=PMC4248886
Michael W. Ferenczy, Eugene O. Major;
Contamination of SVG p12 cells with BK polyomavirus occurred after deposit in the American Type Culture Collection.
J. Virol. 88:12928-12929(2014)

PubMed=25288627; DOI=10.1128/JVI.02153-14; PMCID=PMC4248923
Christine Hanssen Rinaldo, Stian Henriksen, Garth Daryl Tylden, Hans H. Hirsch;
Reply to 'Contamination of SVG p12 cells with BK polyomavirus occurred after deposit in the American type culture collection'.
J. Virol. 88:12930-12930(2014)