L1210小鼠淋巴细胞白血病

小鼠白血病细胞L1210体外悬浮培首先由G.Moore等（1966）和P.Himmelfarb等（1967）报导。此细胞系广泛用于化学因子和天然产物细胞毒活性的常规筛选。 接种裸鼠在21天内100%（5/5）成瘤。 在本库通过支原体检测。

动物种别：小鼠

性别：雌

组织来源：B淋巴细胞白血病

形态：淋巴母细胞；悬浮生长

培养基配方：

90%DMEM(MD0100)+10%胎牛血清(SD0200)+G/A (SD0038)

DMEM完全培养基（MD0101）

气相：空气，95%；二氧化碳，5%。 温度：37℃。

冻存条件：基础培养基+5%DMSO+20%FBS

完全冻存液：免程序降温细胞冻存液（低血清）(SD0001)

声明：产品仅科研使用。

PubMed=18630317; DOI=10.1093/jnci/36.3.405

Moore G.E., Sandberg A.A., Ulrich K.

Suspension cell culture and in vivo and in vitro chromosome constitution of mouse leukemia L1210.

J. Natl. Cancer Inst. 36:405-413(1966)

PubMed=6970130; DOI=10.1002/eji.1830101111

Conzelmann A., Pink R., Acuto O., Mach J.-P., Dolivo S., Nabholz M.

Presence of T 145 on cytolytic T cell lines and their lectin-resistant mutants.

Eur. J. Immunol. 10:860-868(1980)

PubMed=25277546; DOI=10.1186/1471-2164-15-847

Didion J.P., Buus R.J., Naghashfar Z., Threadgill D.W., Morse H.C. III, de Villena F.P.

SNP array profiling of mouse cell lines identifies their strains of origin and reveals cross-contamination and widespread aneuploidy.

BMC Genomics 15:847-847(2014)

PubMed=31220119; DOI=10.1371/journal.pone.0218412

Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B., Gollin S.M., Lewis D.W., Reid Y.A.

Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.

PLoS ONE 14:E0218412-E0218412(2019)